I usually like to hit the Microsoft Tech Ed conference when I can wrangle up the funding to do so.

As the name implies, it's predominantly Microsoft technologies and this year's North America conference will be in Atlanta, Georgia:

http://northamerica.msteched.com

Includes hands-on labs to tinker with the new server technologies and on-site training and certification opportunities in addition to the regular conference sessions.

The inclusion of a NFR TechNet Professional subscription helps increase the BAF (Boss Acceptance Factor) now that they've started that trend.

It used to always be in Orlando, FL but now they're moving it around each year. A shame as the convention center in Orlando was well suited for it and there were tons of lodging options and interesting places to eat IMHO.