If you need to spend a lot of time searching for interesting ones or ones you can answer, you should refine your search criteria. Granted, the in-site search feature doesn't give very good results if you search on everything (better to use site:serverfault.com [query] in Google), but if you use the advanced search options you can narrow it down pretty nicely.
Personally, I don't like ignoring tags, because there are plenty of interesting (IMHO) questions across all the popular tags, but that doesn't stop me from doing targeted searches on only questions containing one tag or another when the mood to read up on a topic strikes me.